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In addition to establishing the role of GSTP1 as a JNK inhibitor, this study also demonstrated the role of GSTP1 in regulating the expression of specific downstream targets of the JNK signaling pathway [7]

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Correlation of the Wnt signaling pathway with ASD pathophysiology has also been demonstrated by the finding that the Wnt pathway is regulated by chromodomain-helicase-DNA-binding protein 8 (CHD8), and de novo mutations of CHD8 are increasingly found in ASD individuals [183–185]